The San Francisco 49ers certainly have had some bad luck so far this season and are dealing with some high-profile injuries.

Andrew Harbaugh of Vikings Wire stops by to talk about the Minnesota Vikings heading into Week 3 against the Houston Texans ...

San Francisco 49ers star tight end George Kittle missed his second straight practice on Friday as ESPN insider Adam Schefter ...

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Brown and Odum allowed Justin Jefferson to get behind them for a 97-yard touchdown pass from Sam Darnold. Both are considered ...

The Niners will perhaps be without arguably their three most important offensive weapons, sidelined stars Christian McCaffrey ...

Week 3 matchup vs. Rams with key injuries to McCaffrey, Samuel, and Kittle, testing their depth in this crucial NFC West ...

An oblique injury has kept Seattle Seahawks running back Kenneth Walker III out of the lineup. He missed their Week 2 win ...

The Rams offense is in shambles. It's missing five starters including both wide receivers and it just scored a measly 10 ...

Jordan Mason hasn’t missed yet and the good times should continue in Week 3 against the Rams, a dreadful defense with an ...

The bruised and battered San Francisco 49ers will need these five players to step up against the short-handed Los Angeles ...