A key finding from these studies was that platelets from mice lacking certain isoforms of the serine/threonine kinase Akt (particularly Akt2) have defects in platelet secretion, fibrinogen binding, ...

Ray Lambert looks at the potential of humanized FcRn mice for evaluating the pharmacokinetics of mAbs. Due to their extraordinary specificity and pharmacokinetic (PK) behavior, human ...

For World of Warcraft players— or MMO enthusiasts in general— the best mice for MMOs can make all the difference in terms of comfort, ease, and performance. Compared to the traditional FPS ...

Positive opinion granted for KEYTRUDA plus chemotherapy for the first-line treatment of adult patients with primary advanced or recurrent endometrial carcinoma who are candidates for systemic therapy, ...

Scientists in China have created a mutant strain of COVID-19 in a lab that has a 100% death rate for mice with human genes.

This important study using engineered mouse models provides a first and compelling demonstration of a pathogenic phenotype associated with lack of expression of p53AS, an isoform of the p53 protein ...

Sep. 18, 2024 — It is crucial for organisms to be able to control which genes are expressed in which cells and when. Naturally occurring chemical modifications of DNA-binding histone proteins ...